This section periodically evalutes the most recent literature on Perthes Disease.
What's new in the Perthes Literature
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Read Morearrow_forward A review of the potential causes of Perthes Disease
To this day, the cause of Perthes disease remains unclear. A great review article available publicly on https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429000/ summarizes prior research studies identifying potential causes and associations with Perthes disease. The article concisely summarizes previously studied associations including various exposures, genetic factors, and socioeconomic factors. There certainly is need for…
Read Morearrow_forward New study demonstrates utility of ultrasound to evaluate hip containment in Perthes Disease
MRI and sonography in Legg-Calvé-Perthes disease: clinical relevance of containment and influence on treatment. Journal of Children’s Orthopaedics, 2018 October Jandl NM, Schmidt T, Schulz M, Rüther W, Stuecker MHF In a recent study, ultrasound measurements were correlated with magnetic resonance imaging (MRI) measurements to evaluate the utility in determing how contained the femoral head was…
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Perthes research output
It takes significant effort to understand, treat, and cure a rare condition such as Perthes disease. As a medical community, we need to advocate for more research efforts, funding, and energy directed to Perthes disease. For 2017, only 47 research studies were published on Perthes disease, as opposed to 1174 studies…
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Is there a role in suppressing inflammation in Perthes disease? A mouse model knockout study.
Article Highlight: Kuroyanagi G, et al., Interleukin-6 deletion stimulates revascularization and new bone formation following ischemic osteonecrosis in a murine model. Bone. 2018 Aug 17. Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/30125727 A recent publication by Kuroyanagi G et al demonstrated some interesting findings. In this study, a mouse model of osteonecrosis of the knee was…
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